LncRNA SNHG15 targets miR-200a-3p affects the proliferation, apoptosis, migration, and invasion of cervical cancer cells.

ABSTRACT:

Background

Cervical cancer is a major challenge facing women's health worldwide. In China, its incidence and mortality rate rank first among female reproductive tract malignancies. SNHG15 has been found and proven to have important functions in many cancers. Related studies have shown that miR-200a-3p plays an important role in tumor development. However, there is little research on how the two are involved in the progression of cervical cancer cells and their potential regulatory systems.

Methods

qRT-PCR was used to detect the expression of LncRNA SNHG15 in human cervical immortalized squamous cells (Ect1/E6E7) and human cervical cancer cell lines (SiHa, HeLa, Caski, C-33 A). Cervical cancer HeLa and SiHa cells were used as the research objects and were divided into NC, GV4

SUBMITTER: Han S 

PROVIDER: S-EPMC12330091 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature