M. caprae in northern Italy: a comprehensive analysis through whole-genome sequencing on the genetic variability in bovine herds.

ABSTRACT: Mycobacterium (M.) bovis and M. caprae are the causative agents of bovine tuberculosis (bTB), which is still a concern due to its health implications and economic impact. Although M. caprae is less prevalent than M. bovis among bovine tuberculosis cases, it has a significant impact on animal health especially in Europe, where it has been isolated from a range of hosts. Starting from spoligotyping and the MIRU-VNTR profile specifically associated with the Lechtal subgroup we decided to process a selection of Italian M. caprae isolates using whole genome sequencing (WGS) to define the phylogenetic relationships between isolates and deepen the understanding of this public health issue. In this study, 20 outbreaks of bovine tuberculosis caused by M. caprae in northern Italy were retrospectivel

SUBMITTER: Bertasio C 

PROVIDER: S-EPMC12330137 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature