Genetic polymorphism of msp2 in Plasmodium falciparum isolates among asymptomatic malaria infections from two ecological settings in Cameroon.

ABSTRACT:

Background

The high genetic diversity of Plasmodium falciparum parasites is one of the challenges for malaria control and elimination in endemic areas. A better knowledge of parasite genotypes circulating in different disease endemic areas could help to optimize local malaria interventions. This study aimed at determining P. falciparum genetic diversity from isolates collected in forest (Mfou) and humid savanna (Tibati) eco-epidemiological settings in Cameroon.

Methods

Dried blood spots collected from asymptomatic individuals in 2018 and 2019 were used to determine the Plasmodium infection status and distinguish the Plasmodium spp. by real-time PCR. Allelic polymorphism of the msp2 gene was assessed in the P. falciparum positive samples by nested PCR followed by capillary el

SUBMITTER: Bouopda-Tuedom AG 

PROVIDER: S-EPMC12330162 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature