Atypical Influenza A(H3N2) Activity Patterns in Germany, 2021-2023, and Characterization of Newly Emerged Virus Clades.

ABSTRACT: The first waves of the COVID-19 pandemic were accompanied by an unprecedented decrease of influenza activity which persisted throughout the 2020/21 and 2021/22 winter seasons. Here, we report on the unusual influenza circulation patterns that followed in the year 2022, which was dominated throughout by A(H3N2) influenza viruses. After a delayed spring wave in 2022, A(H3N2) influenza viruses circulated at low levels throughout the summer and rose to a prominent, prematurely-timed fall/winter wave peaking in December, with highest positivity rates observed in 10-12-years old children. This winter wave ended abruptly with the national school holidays, when positivity rates decreased sharply not only in children but also in other age groups. Genetic analysis of influenza virus hemagglutinin (H

SUBMITTER: Duwe S 

PROVIDER: S-EPMC12330201 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature