Anatomical and histological characterization of the filum terminale in dogs.

ABSTRACT: The filum terminale (FT) remains poorly characterized in the veterinary literature, limiting understanding of its role in spinal cord and nerve root pathologies such as tethered cord syndrome. This study aimed to establish baseline anatomical and histological features of the FT in neurologically normal dogs. Eight adult canine cadavers euthanized for non-neurological reasons were examined. Dissection was performed via dorsal laminectomy (n = 4) and midline sectioning (n = 4). Histological analysis (n = 4) included hematoxylin and eosin, Klüver-Barrera, Masson's trichrome, and Verhoeff-Van Gieson stains, alongside immunohistochemistry for neuron-specific enolase, protein gene product 9.5, and glial fibrillary acidic protein. Grossly, the FT was identified as a direct co

SUBMITTER: Posporis C 

PROVIDER: S-EPMC12330388 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature