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A systematic review of behavioral interventions to improve maternal outcomes for women in the United States at high risk for adverse pregnancy outcomes.


ABSTRACT:

Introduction

Adverse pregnancy outcomes (APOs), including hypertensive disorders, gestational diabetes, and preterm birth, affect 10-20% of U.S. pregnancies and substantially increase long-term cardiovascular disease (CVD) risk. While behavioral interventions during pregnancy may reduce risk factors for APOs, evidence remains limited on which strategies are effective for high-risk women. This systematic review addresses this gap by examining patterns in intervention design, outcome reporting, and areas where research fails to meet the needs of at-risk pregnant populations.

Methods

We searched PubMed and the Cochrane Central Register of Controlled Trials for articles published from January 1, 2005, to June 30, 2024. Following PRISMA guidelines, we included U.S.-based randomiz

SUBMITTER: Phipps JE 

PROVIDER: S-EPMC12330428 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature