Precision functional mapping reveals less inter-individual variability in the child vs. adult human brain.

ABSTRACT: Human brain organization shares a common underlying structure, though recent studies have shown that features of this organization also differ significantly across individual adults. Understanding the developmental pathways that lead to individually unique brains is important for advancing models of cognitive development and neurodevelopmental disorders. Here we use highly personalized precision neuroimaging methods to map brain networks within 12 individual children, ages 8-12 years. We demonstrate fMRI functional connectivity maps that substantially exceed the reliability of traditional techniques, allowing us to measure individual differences after overcoming biases from measurement noise. Children share core functional network topography, with greatest inter-individual variability in a

SUBMITTER: Demeter DV 

PROVIDER: S-EPMC12330735 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature