Global, regional, and national trends in colorectal cancer from 2010 to 2021: an analysis of the global burden of disease study 2021.

ABSTRACT:

Background

Colorectal cancer (CRC) is a major global health challenge due to its high incidence and mortality rates. Understanding its epidemiological trends is essential for informing prevention and intervention strategies.

Methods

This study analyzed global, regional, and national CRC data from 2010 to 2021, focusing on age-standardized incidence, mortality, disability-adjusted life years (DALY), and associated risk factors. Data was sourced from the Global Burden of Disease (GBD) Study 2021 and stratified by the Sociodemographic Index (SDI).

Results

Globally, CRC incidence increased by 35.91% from 1,614,410 cases in 2010 to 2,194,143 cases in 2021. The mortality rate decreased from 13.37 per 100,000 in 2010 to 12.40 per 100,000 in 2021. DALY increased by 23.94%, ye

SUBMITTER: Chen G 

PROVIDER: S-EPMC12330823 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature