Early identification of the efficacy of 0.125% atropine treatment for children with Myopia: A prospective pilot study.

ABSTRACT:

Purpose

This study aimed to investigate whether early axial length (AL) changes in the short term after 0.125% atropine treatment could predict long-term axial elongation in children with myopia.

Methods

This was a prospective cohort study involving children aged 5-15 years with myopia who were treated with 0.125% atropine for myopia control. AL was measured 1-2 months after starting treatment and then every 3 months for follow-up visits. Regression analysis was used to develop a model of AL changes with time. A generalized estimating equation (GEE) model was then used to identify correlations between the early AL changes and long-term AL changes.

Results

Eighty eyes of 40 patients (mean age 8.4 years) were included in the final analysis. The estimation curve of AL ch

SUBMITTER: Chen ZR 

PROVIDER: S-EPMC12331118 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature