Characterisation of serious mental illness trajectories through transdiagnostic clinical features.

ABSTRACT:

Background

Electronic health records (EHRs), increasingly available in low- and middle-income countries (LMICs), provide an opportunity to study transdiagnostic features of serious mental illness (SMI) and its trajectories.

Aims

Characterise transdiagnostic features and diagnostic trajectories of SMI using an EHR database in an LMIC institution.

Method

We conducted a retrospective cohort study using EHRs from 2005-2022 at Clínica San Juan de Dios Manizales, a specialised mental health facility in Colombia, including 22 447 patients with schizophrenia (SCZ), bipolar disorder (BPD) or severe/recurrent major depressive disorder (MDD). Using diagnostic codes and clinical notes, we analysed the frequency of suicidality and psychosis across diagnoses, patterns of diagnostic

SUBMITTER: De la Hoz JF 

PROVIDER: S-EPMC12331236 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature