Liver tumor imaging staging: a multi-institutional study of a preoperative staging tool for hepatocellular carcinoma.

ABSTRACT:

Background & aims

The current staging system has limitations in preoperatively assessing hepatocellular carcinoma (HCC) and in precise detailed treatment allocation. This study aims to propose a new Liver Tumor Imaging Staging (LTIS) method for HCC.

Methods

1295 patients who underwent CT or MRI and curative liver resection during January 2012 and October 2020 were retrospectively recruited from three independent institutions. All images were interpreted by two abdominal and a board-certified radiologist. LTIS was designed to discriminate low-grade (absence of microvascular invasion [MVI] and Edmondson-Steiner grade III/IV), intermediate (MVI + or Edmondson-Steiner grade III/IV but not both) and high-grade HCC (MVI + and Edmondson-Steiner grade III/IV) upon CT and MRI. Model

SUBMITTER: Liu Q 

PROVIDER: S-EPMC12331851 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature