In-silico receptor interactions, phytochemical fingerprint and biological activities of Matricaria chamomilla flower extract and the main components.

ABSTRACT: In this study, total phenolic and flavonoid content, quantitative phenolic analysis, in-vivo, in-vitro and in-silico biological activities of Matricaria chamomilla flower extracts collected from Bulancak (Giresun) were investigated. Phenolic content was determined by LC-MS/MS and antioxidant, antibacterial, antifungal, antigenotoxic and anti-inflammatory activities of the extract and the main components were investigated. Caffeic acid, quercetin and kaempferol were detected as major compounds in the flower extract by LC-MS/MS analysis and the detected levels were 165.085 mg/kg, 112.673 mg/kg and 67.417 mg/kg, respectively. The DPPH radical scavenging activity of M. chamomilla flower extract ranged from 12.4 to 81.1%, while superoxide anion inhibition was observed between 10.6 and 65.8%. Ev

SUBMITTER: Ayhan BS 

PROVIDER: S-EPMC12331924 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature