Exploring the relationship between circadian syndrome, serum uric acid levels, and hyperuricemia: evidence from NHANES 2005-2018.

ABSTRACT: Hyperuricemia is closely linked to metabolic diseases and cardiovascular conditions, while circadian syndrome (CircS) plays a pivotal role in metabolic syndrome (MetS) and its related disorders. This study examines the relationship between CircS, serum uric acid (SUA) levels, and the risk of hyperuricemia using data from the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2018. Weighted multivariable linear and logistic regression analyses were employed to assess the relationships between CircS, its components, SUA levels, and the risk of hyperuricemia, supplemented by subgroup analyses and interaction tests to understand the influence of other risk factors. Restricted cubic spline (RCS) regression was utilized to investigate potential nonlinear relationships. The st

SUBMITTER: Mao H 

PROVIDER: S-EPMC12331993 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature