Gut microbiota maturation and early behavioral and cognitive development.

ABSTRACT: The presence of gut microbiota-brain-axis has been widely reported. However, few studies have focused on uncovering the potential associations during a time-period that our brain and gut microbiota undergo rapid maturation. We evaluated the potential associations between characteristics of gut microbiota and cognition and temperament using an accelerated longitudinal design in typically developing children over 0-3 years of age. Specifically, we extracted gut microbiota characteristics at three scale levels: diversity measures, microbial networks, and subject-wise longitudinal trajectory features, shedding light on how associations between cognition/temperament and gut microbiota may differ at global (diversity), ecological (microbial networks) and subject-wise levels. Our findings illustr

SUBMITTER: Zhu Z 

PROVIDER: S-EPMC12332070 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature