Towards an Informed Choice of Diffusion MRI Image Contrasts for Cerebellar Segmentation.

ABSTRACT: The fine-grained segmentation of cerebellar structures is an essential step towards supplying increasingly accurate anatomically informed analyses, including, for example, white matter diffusion magnetic resonance imaging (MRI) tractography. Cerebellar tissue segmentation is typically performed on structural MRI data, such as T1-weighted data, while connectivity between segmented regions is mapped using diffusion MRI tractography data. Small deviations in structural to diffusion MRI data co-registration may negatively impact connectivity analyses. Reliable segmentation of brain tissue performed directly on diffusion MRI data helps to circumvent such inaccuracies. Diffusion MRI enables the computation of many image contrasts, including a variety of tissue microstructure maps. While multiple

SUBMITTER: Legarreta JH 

PROVIDER: S-EPMC12332183 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature