From triple-mode network to triple-layered model - novel insights in social cognition.

ABSTRACT: Modern studies have revealed various pathophysiological mechanisms underlying neurodegenerative dementias. Among these, disruption of the "triple mode network" is widely recognized as a pivotal common pathway leading to the development of the neurodegenerative dementias including Alzheimer's dementia. Contemporary studies have shown strong association of impaired social cognition with various dementias. However, how the misaligned social cognition leads to neurocognitive decline is still enigmatic. Herein, the authors introduce the term "triple-layered model of social cognition", which encompasses the three pillars, that is, the basic "core cognitive constructs", the value-based "higher-level cognitive constructs", and instinct-driven "lower-level cognitive constructs (i.e., the bottom cir

SUBMITTER: Dubey S 

PROVIDER: S-EPMC12332737 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature