Surface-Modified Nanozymes for Enhanced and Selective Catalysis.

ABSTRACT: Surface-modified catalytic nanoparticles (nanozymes) are introduced as hybrid nanoparticles overcoming basic limitations associated with bare nanozymes that include moderate catalytic turnovers, lack of substrate selectivity and chiroselectivity, and poor or nonselective permeabilities into biomembrane. This review introduces aptamer-modified nanozymes, receptor (cyclodextrins)- or ligand (amino acids, peptides)-functionalized catalytic nanoparticles, and molecularly imprinted polymer-coated nanozymes as hybrid frameworks improving the catalytic properties and selective/chiroselective functions of the nanozymes. Binding of the reaction substrates to the aptamers, ligands, or molecular-imprinted sites, by affinity interactions, concentrates the substrates in spatial proximity to the nanozym

SUBMITTER: Chen X 

PROVIDER: S-EPMC12332837 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature