The Raman Map of the Human Cell.

ABSTRACT: Cell activity is governed by its subcellular compartments, each playing a specialized role essential to the overall function. Among various methods used for cell analysis, Raman microscopy is unique, enabling the study of single living cells at a submicron resolution. It is used for phenotyping of cells, monitoring the mechanisms of various stimuli or drugs, or tracking cell metabolism in real time. However, localizing specific organelles and identifying their components remain a challenge. Therefore, the "Raman Map of the Cell" aims to provide a reliable method for subcellular analysis and cataloging the Raman spectra of prominent cell organelles. In this study, we focused on endothelial cells due to their prevalence and widespread application in biomedical research. Using Raman im

SUBMITTER: Nowakowska AM 

PROVIDER: S-EPMC12332844 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature