Dosimetric and robustness evaluation of biaxially rotational dynamic radiation therapy with robust optimization.

ABSTRACT:

Background

Studies suggest that integrating robust planning and noncoplanar volumetric modulated arc therapy (VMAT) may be a useful strategy for maximizing the benefits of dose delivery while maintaining resilience to uncertainty; however, the robustness of target coverage and the dose-sparing performance for organs at risk of techniques that combine dynamic trajectory irradiation and robust planning have not been fully investigated.

Purpose

We aimed to evaluate the combination of biaxially rotational dynamic radiation therapy (BROAD-RT) with robust planning to improve the dosimetric outcomes and robustness of head and neck cancer (HNC) radiation therapy.

Methods

We retrospectively analyzed 10 patients with oropharyngeal and hypopharyngeal cancers who were treated wit

SUBMITTER: Hirotaki K 

PROVIDER: S-EPMC12332889 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature