Alkane Dehydrogenation and H/D Exchange by a Cationic Pincer-Ir(III) Hydride: Cooperative C-H Addition and β-H Elimination Modes Induce Anomalous Selectivity.

ABSTRACT: We report that the cationic iridium complex (^iPrPCP)IrH⁺ catalyzes the transfer-dehydrogenation of alkanes to give alkenes and hydrogen isotope exchange (HIE) of alkanes and arenes. Contrary to established selectivity trends found for C-H activation by transition metal complexes, strained cycloalkanes, including cyclopentane, cycloheptane, and cyclooctane, undergo C-H addition much more readily than n-alkanes, which in turn are much more reactive than cyclohexane. Aromatic C-H bonds also undergo H/D exchange much less rapidly than those of the strained cycloalkanes, but much more favorably than cyclohexane. The order of reactivity toward dehydrogenation correlates qualitatively with the reaction thermodynamics, but the magnitude is much greater than can be expl

SUBMITTER: Parihar A 

PROVIDER: S-EPMC12333025 | biostudies-literature | 2025 Mar

REPOSITORIES: biostudies-literature