Basicity-Controlled C-H Bond Activation by a Structurally Characterized Ni(III)-Hydroxo Complex.

ABSTRACT: The selective oxidation of strong C-H bonds remains a central challenge in synthetic chemistry, in part due to the elusive nature of active oxidants and their underlying mechanisms. Herein, we report the isolation and complete characterization of a room-temperature-stable mononuclear Ni(III)-hydroxo complex, [Na(15c5)][Ni(PS3″)(OH)] ([Na(15c5)][2]), supported by a tris(benzenethiolato)phosphine ligand derivative. The X-ray crystallographic structure of 2 reveals a trigonal bipyramidal Ni(III) center, in which the coordinated hydroxo ligand is stabilized by secondary coordination sphere interactions. Complex 2 displays hydrogen atom transfer (HAT) reactivity toward strong C-H bonds, including that in cyclohexane (BDE = 99.5 kcal mol^-1). Kinetic studies

SUBMITTER: Pan HR 

PROVIDER: S-EPMC12333028 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature