Association between glycated hemoglobin/high-density lipoprotein ratio and nonalcoholic fatty liver disease in a U.S. nondiabetic population: a cross-sectional study based on NHANES 2017-2020 data.

ABSTRACT:

Aims

The purpose of this research was to explore the relationship between the glycated hemoglobin/high-density lipoprotein (HbA1c/HDL-C) ratio and nonalcoholic fatty liver disease (NAFLD) in non-diabetic adults in the United States.

Methods

Using pertinent variables gathered from the 2017-2020 National Health and Nutrition Examination Survey (NHANES) database, we performed a cross-sectional study including 5,485 adult U.S. citizens. Data were analyzed using multifactor logistic regression, smoothed curve fitting, subgroup, and interaction analyses.

Results

Among the 5485 individuals included, there was a significant positive correlation between NAFLD and HbA1c/HDL-C ratio. After adjusting for all covariates, the probability of having NAFLD increased significantly for

SUBMITTER: Zheng X 

PROVIDER: S-EPMC12333052 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature