Stimulated cytokine production, attachment, and emotional well-being in dementia spousal caregivers.

ABSTRACT:

Background

Proinflammatory cytokine production may be related to poor emotional adjustment in dementia spousal caregivers. People who display attachment insecurity may be at increased risk for adverse caregiving experiences and poor psychosocial outcomes.

Objective

This study aimed to understand whether proinflammatory cytokine production was associated with anticipatory grief, caregiver burden, and depressive symptoms and whether those relationships were stronger for caregivers higher on attachment anxiety or avoidance.

Method

A sample of 103 dementia spousal caregivers provided self-report data on demographics, health information, and psychosocial outcomes. We also determined lipopolysaccharide-induced whole-blood interleukin-6, interleukin-1β, tumor necrosis factor

SUBMITTER: Argueta DL 

PROVIDER: S-EPMC12333394 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature