Doubly Robust Estimation of Marginal Cumulative Incidence Curves for Competing Risk Analysis.

ABSTRACT: Covariate imbalance between treatment groups makes it difficult to compare cumulative incidence curves in competing risk analyses. In this paper, we discuss different methods to estimate adjusted cumulative incidence curves, including inverse probability of treatment weighting and outcome regression modeling. For these methods to work, correct specification of the propensity score model or outcome regression model, respectively, is needed. We introduce a new doubly robust estimator, which requires correct specification of only one of the two models. We conduct a simulation study to assess the performance of these three methods, including scenarios with model misspecification of the relationship between covariates and treatment and/or outcome. We illustrate their usage in a cohort study of

SUBMITTER: van Hage P 

PROVIDER: S-EPMC12333911 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature