Immunosuppression variably impacts outcomes for patients hospitalized with COVID-19: A retrospective cohort study.

ABSTRACT: Adults with immunosuppression are more likely to develop severe COVID-19 than adults without immunosuppression. Less is known about differences in outcomes for adults with immunosuppression who are hospitalized with COVID-19. A retrospective cohort study of adults hospitalized with COVID-19 at Northwestern Medicine hospitals between 03/01/2020 and 05/31/2022 was performed. Regression analyses were performed comparing in-hospital mortality, intensive care unit (ICU) admission, oxygenation requirements, and hospital/ICU length of stay among patients without immunosuppression (n = 9079) and patients with immunosuppression (n = 873). Patients with immunosuppression had significantly higher mortality than patients without immunosuppression (OR: 1.33, 95% CI: 1.11-1.60). This effect was even str

SUBMITTER: Guggilla V 

PROVIDER: S-EPMC12334029 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature