Disentangling the neural underpinnings of response inhibition in disruptive behavior and co-occurring ADHD.

ABSTRACT: While impaired response inhibition has been reported in attention-deficit/hyperactivity disorder (ADHD), findings in disruptive behavior disorders (DBDs) have been inconsistent, probably due to unaccounted effects of co-occurring ADHD in DBD. This study investigated the associations of behavioral and neural correlates of response inhibition with DBD and ADHD symptom severity, covarying for each other in a dimensional approach. Functional magnetic resonance imaging data were available for 35 children and adolescents with DBDs (8-18 years old, 19 males), and 31 age-matched unaffected controls (18 males) while performing a performance-adjusted stop-signal task. No significant association was found between behavioral performance and symptom severities. However, contrasting successful inhibitio

SUBMITTER: Saracaydın G 

PROVIDER: S-EPMC12334431 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature