Carbetocin versus oxytocin in prevention of postpartum hemorrhage after cesarean delivery in high-risk women. A systematic review and meta-analysis.

ABSTRACT:

Objectives

To assess the value of carbetocin in prevention of postpartum hemorrhage (PPH) after Cesarean delivery (CD).

Search strategy

Screening of PubMed, Web Of Science, Scopus, register clinical trials registry and Google scholar from inception to December 2023. The keywords used included postpartum hemorrhage, intraoperative blood loss, postoperative blood loss, Cesarean delivery and their MeSH terms.

Selection criteria

All RCTs that compared carbetocin to oxytocin in women undergoing CD with risk factor for PPH. Fourteen studies including 3068 participants. Thirteen were written in English and one in Polish.

Data collection and analysis

The extracted data included location of the trial, number of centers involved in recruitment, the number of participants

SUBMITTER: El-Goly NA 

PROVIDER: S-EPMC12334512 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature