Lichen Planus Following COVID-19 Infection and Vaccination. Matched Case-Control Study.

ABSTRACT:

Background

New-onset lichen planus (LP) development following COVID-19 infection/vaccination is reported. Since case series cannot be used to study exposure-outcome associations, we designed this matched case-control study to investigate whether COVID-19-related events and de novo LP are associated.

Methods

Patients with histologically confirmed LP, newly diagnosed at the National Research Center of Dermato-Venereology of Moscow (September 2020-December 2022), were considered. Sex/age/ethnicity-matched controls attending the same Center in the same period for consultations on conditions unrelated to LP were selected. Cases/controls with known LP trigger factors were excluded. COVID-19-related events were: symptomatic COVID-19 (PCR-confirmed), and COVID-19 vaccination (viral

SUBMITTER: Arduino PG 

PROVIDER: S-EPMC12334811 | biostudies-literature | 2025 May

REPOSITORIES: biostudies-literature