Vascular Risk Factors and 1-Year Cognitive Change Among Individuals With Traumatic Brain Injury.

ABSTRACT:

Importance

Traumatic brain injury (TBI) and vascular risk factors are associated with cognitive impairment, but it is unknown if individuals with vascular risk factors experience worse cognitive outcomes after TBI.

Objective

To evaluate cognitive function among patients with TBI with vs without comorbid preinjury vascular risk factors.

Design, setting, and participants

This prospective cohort study examined individuals with TBI enrolled in the Transforming Research and Clinical Knowledge in TBI (TRACK-TBI) Study between February 26, 2014, and August 8, 2018, with a 1-year follow-up. Analyses were conducted February 26, 2024, to May 29, 2025.

Exposures

Vascular risk factors (ie, hypertension, diabetes, hyperlipidemia, and smoking).

Main outcomes and measures<

SUBMITTER: Schneider ALC 

PROVIDER: S-EPMC12334961 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature