Probiotic potential of ginseng derived Lacticaseibacillus rhamnosus strains with hypocholesterolemic, antioxidant and antibacterial activities.

ABSTRACT: Cardiovascular diseases remain one of the leading causes of mortality among adults worldwide, with elevated blood lipid levels serving as a key modifiable risk factor. This study aimed to investigate the probiotic potential of lactic acid bacteria (LAB) isolated from ginseng sprouts (Panax ginseng Meyer) cultivated under smart-farming conditions, with a particular emphasis on their cholesterol-lowering properties. Out of 485 isolates, five strains of Lacticaseibacillus rhamnosus were selected based on superior in vitro performance and identified through 16 S rRNA sequencing and phylogenetic analysis. The selected strains demonstrated high tolerance to simulated gastrointestinal conditions (pH 3.0, 0.3% bile salts), with survival rates ranging from 98 to 99%. In addition, they exhibited rob

SUBMITTER: Ahmed E 

PROVIDER: S-EPMC12335598 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature