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ABSTRACT: Objective
To determine if implementing the IFCN criteria to define interictal epileptiform discharges (IEDs) improves expert inter-rater reliability (IRR) and diagnostic performance.Methods
Nine EEG experts rated the same 200 candidate IEDs (100 expert-consensus, 100 epilepsy monitoring unit [EMU]-validated) as epileptiform or not, in random order, in two rounds separated by at least 30 days. During the second round, raters additionally selected the applicable IFCN criteria for each candidate IED.Results
Overall, there were no major differences in performance (AUC; 0.90 vs. 0.91) or IRR (AC1; 0.48 vs. 0.47) between both Parts; nor was there a major difference in calibration within the expert-consensus dataset (median absolute calibration index; 35.5 vs. 30.0). Simil
SUBMITTER: Yuan D
PROVIDER: S-EPMC12335889 | biostudies-literature | 2025 May
REPOSITORIES: biostudies-literature