Long-Term (5-Years) Outcomes of Current Drug-Eluting Stents in Percutaneous Coronary Intervention: A Network Meta-Analysis of Randomized Controlled Trials.

ABSTRACT:

Background

Various drug-eluting stents (DES) are currently used for percutaneous coronary intervention (PCI). However, long-term trials reveal inconsistent results in head-to-head comparisons.

Aims

To conduct a network meta-analysis of relevant trials to assess the performance of different DES currently used in PCI.

Methods

We systematically searched major databases for randomized controlled trials (RCTs) reporting 5-year outcomes of currently used DES and conducted a network meta-analysis using a frequentist random-effects model with odds ratios (ORs) as effect measures. DES were ranked by P-scores across several outcomes, with definite/probable stent thrombosis as the primary outcome. Statistical analyses were conducted in R software (v4.4.1), with significance set

SUBMITTER: Goyal A 

PROVIDER: S-EPMC12336763 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature