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ABSTRACT: Objective
Anorexia nervosa, a restrictive eating disorder that is most commonly seen in females, is associated with alterations in gray matter (GM) and white matter (WM) structures. However, little is known about how restrained eating (RE) and the body mass index-standard deviation score (BMI-SDS) are related to brain morphology and whether sex differences exist in the general pediatric population.Method
Participants were 9-year-old girls and boys (n = 2729) from the population-based Generation R Study. BMI-SDS was calculated by adjusting BMI for sex and age, using Dutch growth curves. RE is measured with the Dutch Eating Behavior Questionnaire. All children underwent structural magnetic resonance imaging, and brain volumes were calculated using FreeSurfer.Results
B
SUBMITTER: Steegers CPM
PROVIDER: S-EPMC12336774 | biostudies-literature | 2025 Aug
REPOSITORIES: biostudies-literature