Effectiveness and Safety of Myval Versus Other Transcatheter Valves in Patients Undergoing TAVI: A Meta-Analysis.

ABSTRACT: Transcatheter aortic valve implantation (TAVI) has changed the treatment of aortic stenosis. The Myval transcatheter heart valve (THV), a novel balloon-expandable THV, has shown promising outcomes. Our aim is to compare the comparative safety and effectiveness of Myval THV against established THVs, such as Sapien and Evolut. A systematic review and meta-analysis was conducted, comparing the Myval THV with other contemporary THVs. Primary endpoints were periprocedural, 30-day and 1-year all-cause mortality. Seven studies involving 3106 patients (1027 Myval; 2079 other THVs) were included. No significant differences were observed in the primary endpoints. Myval demonstrated higher procedural success (RR: 1.04, 95% CI: 1.01-1.07, I² = 29%) and lower rates of permanent pacemaker implantation (

SUBMITTER: Apostolos A 

PROVIDER: S-EPMC12336787 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature