Beyond language: empathy and emotion recognition deficits in primary progressive aphasias.

ABSTRACT: Although primary progressive aphasia (PPA) is considered a language disorder, increasing evidence points to the presence of social cognition impairments in PPA variants. The aims of this study were to explore empathy and emotion recognition deficits in the three PPA variants (sv-PPA, lv-PPA, nfv-PPA) and to identify their neural correlates. Eleven sv-PPA, 34 lv-PPA,11 nfv-PPA patients and 34 healthy controls (HC) were included in this study. Empathy was explored with the Interpersonal Reactivity Index (IRI) (Perspective Taking - PT, Fantasy - FT, Empathic Concern - EC, Personal Distress - PD), rated by caregivers before (T0) and after (T1) the onset of cognitive symptoms. Emotion recognition was evaluated with the Ekman 60Faces (EK-60F) Test and metabolic activity with [18F]FDG-PET. In all

SUBMITTER: Giacomucci G 

PROVIDER: S-EPMC12337676 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature