Subpopulations with frequent healthcare barriers have increased risk of sexually transmitted infections and dropping out from HIV preexposure prophylaxis care.

ABSTRACT:

Objective

Certain subpopulations (i.e., <25 years, transgender, sex worker, uninsured or migrant) were prioritized for inclusion in the Dutch preexposure prophylaxis (PrEP) pilot. We compared incidence of sexually transmitted infections (STI) during and drop-out from HIV PrEP care between prioritized and nonprioritized subpopulations.

Design

Retrospective longitudinal study using routinely collected data at the Centre for Sexual Health Amsterdam, 2019-2024.

Methods

We modelled incidence rates (IR) for any STI while on PrEP using Poisson regression, adjusting for testing frequency and calendar time. We modelled the probability of early loss-to-follow-up (LTFU) (i.e., no PrEP follow-up visit within 12 months of enrolment) using logistic regression, adjusting for sexual

SUBMITTER: Wijstma ES 

PROVIDER: S-EPMC12337923 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature