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Clinical and microbiological features of Inquilinus sp. isolates from five patients with cystic fibrosis.


ABSTRACT: Patients with cystic fibrosis (CF) may be colonized with unusual gram-negative bacilli whose identification is difficult and clinical impact unclear. We describe the clinical and microbiological features of five colonizations with organisms belonging to the recently described genus Inquilinus in CF patients. Isolates were identified from Burkholderia cepacia selective medium by means of 16S rRNA analysis. All of them were resistant to colistin, penicillins, cephalosporins, and monobactams but exhibited a remarkable susceptibility to imipenem. One of the five patients was transiently colonized with a nonmucoid isolate, whereas the four other patients were persistently colonized over the period of follow-up (8 to 21 months) with mucoid isolates. Pulsed-field gel electrophoresis of SpeI-diges

SUBMITTER: Chiron R 

PROVIDER: S-EPMC1233925 | biostudies-literature | 2005 Aug

REPOSITORIES: biostudies-literature