Comparison between sequence analysis and a line probe assay for testing genotypic resistance of human immunodeficiency virus type 1 to antiretroviral drugs.

ABSTRACT: The purpose of this study was to compare a line probe assay (LiPA) with sequence analysis for the detection of mutations conferring resistance to nucleoside and non-nucleoside inhibitors in human immunodeficiency reverse transcriptase and protease inhibitors. The limitations for interpreting LiPA make it unacceptable for routine clinical practice.

SUBMITTER: Garcia-Bujalance S 

PROVIDER: S-EPMC1233962 | biostudies-literature | 2005 Aug

REPOSITORIES: biostudies-literature