Short-term oral estriol for cervical stenosis, labial adhesion, and challenging intrauterine contraceptive device removal in postmenopausal women: A case series.

ABSTRACT: Cervical stenosis and labial adhesion associated with vulvovaginal atrophy (VVA) obstruct access to the uterine cavity and reduce quality of life. Removal of intrauterine contraceptive devices (IUD) is challenging without adequate cervical ripening in postmenopausal women. Local estrogen administration and mechanical dilatation are performed to improve these conditions; however, alternatives are necessary for those who have difficulty with vaginal medication. We report five cases of short-term oral estriol administration in postmenopausal women. Case 1 was a 60-year-old woman with an endometrial lesion requiring differentiation from malignancy. Endometrial examination was challenging because of cervical stenosis and VVA. Case 2 was an 82-year-old woman who had a giant ovarian tumor with fl

SUBMITTER: Yuge A 

PROVIDER: S-EPMC12340359 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature