Maternal dietary fish oil developmentally programs adipogenic development in the broiler chick embryo.

ABSTRACT: Our objective was to identify the molecular mechanisms through which fish oil, a source of omega-3 polyunsaturated fatty acids (n-3 PUFA) in the hen diet influence adipose development in chick embryo. Broiler-breeder hens (n = 30/diet) were fed diets containing 2.3% of either fish oil or soybean oil (n-6 PUFA control) for four weeks. Fertilized eggs (n = 40/diet) from maternal fish oil (MFO) and soybean oil (MSO) were randomly collected and incubated to embryonic ages (E) 14, E16, and E20. Fatty acid profiles revealed that MFO significantly enriched yolk and subcutaneous adipose tissue in EPA and DHA. This difference was reflected in adipose tissue morphology, as histological analysis showed that MFO significantly reduced adipocyte size and increased the frequency of small adipocytes at ea

SUBMITTER: Kim M 

PROVIDER: S-EPMC12341610 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature