CT angiography of the carotid body: bridging the gap between normal and neoplastic lesions.

ABSTRACT:

Objective

Sympathetic nervous system hyperactivation in chronic conditions, such as hypertension and metabolic syndrome, can lead to carotid body (CB) hyperplasia, potentially mimicking small carotid body tumours (CBTs) in radiological evaluations. This study aimed to investigate CT angiography (CTA) findings to differentiate CBTs from non-neoplastic CBs.

Methods

Patients were categorized into CBT and non-neoplastic CB groups. Demographics (smoking status, hypertension, diabetes mellitus), shape, dimensions, volume, and density (including standard deviations) were assessed. Density ratios were calculated using CB/CBT and ipsilateral common carotid artery density. Diagnostic performance was evaluated via ROC analysis, and logistic regression identified factors associated with

SUBMITTER: Yılmazer Zorlu SN 

PROVIDER: S-EPMC12341684 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature