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Ultrasonic-assisted refinement of domesticated-wild silk protein composite nanofibers: enhancing miscibility, uniformity, and functionality via ionic liquid processing.


ABSTRACT: Silk fibroin is highly regarded for its exceptional biocompatibility, degradability, and mechanical properties, making it a valuable material in the field of tissue engineering. Ultrasound technology, recognized as a safe and efficient physical method, enables precise manipulation of material microstructures and macroscopic properties, which is essential for the development of innovative high-performance biomaterials. This study aims to enhance the solution miscibility, fiber uniformity, and properties of silk-based protein nanofiber materials by employing a silk-silk composite approach. The method involved air-spinning of Tussah silk fibroin (TSF) and Bombyx mori silk fibroin (BSF) blends through ionic liquid dissolution, combined with ultrasound-assisted processing. Comprehensive charact

SUBMITTER: Zhuang X 

PROVIDER: S-EPMC12341723 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature