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An upgraded nuclease prime editor platform enables high-efficiency singled or multiplexed knock-in/knockout of genes in mouse and sheep zygotes.

ABSTRACT:

SUBMITTER: Mao W 

PROVIDER: S-EPMC12342182 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature

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An upgraded nuclease prime editor platform enables high-efficiency singled or multiplexed knock-in/knockout of genes in mouse and sheep zygotes.

Mao Weijia W   Wang Pei P   Zhou Lei L   Li Dongxu D   Li Xiangyang X   Lou Xin X   Huang Xingxu X   Wang Feng F   Zhang Yanli Y   Liu Jianghuai J   Wan Yongjie Y  

Protein & cell 20250801 8

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