IgA Nephropathy and the Risk of Primary Infections: A Swedish Population-Based Cohort Study.

ABSTRACT:

Introduction

IgA nephropathy is the most common primary kidney disease in the world and has a highly variable clinical presentation. While studies have indicated a link between glomerular disease and infections, large-scale studies on IgA nephropathy are missing.

Methods

In our study, IgA nephropathy was defined as having a kidney biopsy record 1997-2011 in Sweden. Each IgA nephropathy patient was matched with five reference individuals based on age, sex, calendar year, and county of residence. We excluded individuals with earlier organ transplants, HIV, immunodeficiency, or end-stage kidney disease. Linear and Cox regressions, adjusted for age, sex, education, and diabetes, were performed to analyze total infections and antimicrobial treatments in both patients and referenc

SUBMITTER: Rehnberg J 

PROVIDER: S-EPMC12342696 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature