Five-Year Time Profiles of Clearances of Different Uremic Solutes in Incident Peritoneal Dialysis Patients.

ABSTRACT:

Introduction

Different uremic solutes have varying degrees of clearances owing to different chemical properties and the pathological and physiological changes in the kidneys and peritoneum.

Methods

The 5-year time profiles of renal, peritoneal, and total clearances of creatinine, urea nitrogen (UN), uric acid (UA), trimethylamine n-oxide (TMAO), phosphate, beta-2-microglobulin (β2-MG), interleukin-6 (IL-6), indoxyl sulfate (IS), and p-cresol sulfate (PCS) were investigated in 64 peritoneal dialysis (PD) patients. The patients were divided into an early start and a late start group according to baseline estimated glomerular filtration rate to investigate the effect of dialysis initiation timing on uremic solutes clearances. Patients were also divided into incremental

SUBMITTER: Ji J 

PROVIDER: S-EPMC12342698 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature