Coordinated Meta-Storms enables comparison of million-level microbiomes.

ABSTRACT:

Motivation

Phylogeny-based distance serves as the foundation in the evaluation of microbiome beta diversity. However, the exponential growth of data volume has recently introduced substantial computational challenges, while current methods remain limited in their scalability and efficiency.

Results

To solve these issues, we introduce Coordinated Meta-Storms (CMS), a novel approach for large-scale microbiome phylogeny-based distance calculation. CMS incorporates a dynamic multiple Graphics Processing Unit architecture based on a self-adaptive data decomposition strategy and optimization, which empowers pairwise comparison of million-level microbiomes within 40 h on a single computing node.

Availability and implementation

Coordinated Meta-Storms is implemented by CUDA,

SUBMITTER: Wang M 

PROVIDER: S-EPMC12342987 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature