Tsbrowse: an interactive browser for ancestral recombination graphs.

ABSTRACT:

Summary

Ancestral recombination graphs (ARGs) represent the interwoven paths of genetic ancestry of a set of recombining sequences. The ability to capture the evolutionary history of samples makes ARGs valuable in a wide range of applications in population and statistical genetics. ARG-based approaches are increasingly becoming a part of genetic data analysis pipelines due to breakthroughs enabling ARG inference at biobank-scale. However, there is a lack of visualization tools, which are crucial for validating inferences and generating hypotheses. We present tsbrowse, an open-source, web-based Python application for the interactive visualization of the fundamental building blocks of ARGs, i.e. nodes, edges and mutations. We demonstrate the application of tsbrowse to various data so

SUBMITTER: Karthikeyan S 

PROVIDER: S-EPMC12342996 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature