Longitudinal relationships between daily activity and hippocampal atrophy in Japanese dwellers.

ABSTRACT:

Background

The relationship between physical activity and hippocampal volume is important; however, most studies have used questionnaires to measure physical activity. We aimed to determine whether maintaining high levels of daily physical activity measured by an accelerometer reduces hippocampal atrophy in community-dwelling adults.

Methods

This cohort study used data from community-dwelling adults aged ≥60 years who participated in the National Institute for Longevity Sciences Longitudinal Study of Aging, which is a population-based prospective cohort study of approximately 2300 Japanese adults. Tertiles of step count, light-intensity physical activity, and moderate-to-vigorous-intensity physical activity (MVPA) were measured using accelerometers. Changes in the hippocampa

SUBMITTER: Yuki A 

PROVIDER: S-EPMC12343067 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature