Active Seizures Predict Worse Instrumental Activities of Daily Living in Individuals With Normal Cognition and Dementia.

ABSTRACT:

Objectives

Cognitive disorders are common in older persons with seizures (PWS). Cognitive disorders are often associated with impaired Instrumental Activities of Daily Living (IADLs). However, the effects of seizures on IADLs remain unexplored. This study (9/2005-3/2024) from 42 US Alzheimer's Disease Research Centers examined baseline and longitudinal IADL decline in cognitively normal and cognitively impaired participants grouped as active seizures (past 12 months), remote seizures (history but none in 12 months), and controls (no seizures).

Methods

Pfeffer Functional Activities Questionnaire (FAQ) measured IADLs. ANOVA compared individual and total FAQ by seizure and cognitive status. Multivariable linear regression adjusted FAQ for seizure status, age, sex, and education

SUBMITTER: Zawar I 

PROVIDER: S-EPMC12343324 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature