Cross-sectional and longitudinal changes in category selectivity in visual cortex following pediatric cortical resection.

ABSTRACT: The topographic organization of category-selective responses in human ventral occipitotemporal cortex (VOTC) and its relationship to regions subserving language functions is remarkably uniform across individuals. This arrangement is thought to result from the clustering of neurons responding to similar inputs, constrained by intrinsic architecture and tuned by experience. We examine the malleability of this organization in individuals with unilateral resection of VOTC during childhood for the management of drug-resistant epilepsy. In cross-sectional and longitudinal functional imaging studies, we compare the topography and neural representations of 17 category-selective regions in individuals with a VOTC resection, a 'control patient' with a resection outside VOTC, and typically developing

SUBMITTER: Liu TT 

PROVIDER: S-EPMC12343967 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature